Unfold.jl

Beta Toolbox to perform linear regression on biological signals.

Docs

This tool combines mass-univariate linear (mixed) models with overlap correction.

This kind of overlap correction is also known as encoding modeling, linear deconvolution, Temporal Response Functions (TRFs) and probably under other names. fMRI models with HRF-basis functions are also supported.

Relation to Unfold (matlab)

The matlab toolbox is recommended for research work. It is richer in features, better documented and tested.

The julia toolbox is a type of research-playground, but offers LinearMixedModel support.

Feature Unfold unmixed Unfold.jl
overlap correction x x x
non-linear splines x x x
plotting tools x UnfoldMakie.jl - beta
sanity checks x
tutorials x x
speed x x
unittests x x
HRF (fMRI) basis x
mix different basisfunctions x
different timewindows per event x
mixed models x x
item & subject effects x x
decoding back2back regression

Install

]add Unfold

Usage

For a quickstart:

f = @formula 0~1+condA
fLMM = @formula 0~1+condA+(1|subject) + (1|item)
events::DataFrame
data::Array{Float64,2}
epochs::Array{Float64,3} # channel x time x epochs (n-epochs == nrows(events))
times = range(0,length=size(epochs,3),step=1/sampling_rate)

basisfunction::Unfold.BasisFunction
basis = firbasis(τ=(-0.3,0.5),srate=250)
  1. Timeexpansion No, Mixed No : fit(UnfoldModel,Dict(Any=>(f,times)),evts,data_epoch)
  2. Timeexpansion Yes, Mixed No : fit(UnfoldModel,Dict(Any=>(f,basis)),evts,data)
  3. Timeexpansion No, Mixed Yes : fit(UnfoldModel,Dict(Any=>(fLMM,times)),evts,data_epoch)
  4. Timeexpansion Yes, Mixed Yes: fit(UnfoldModel,Dict(Any=>(fLMM,basis)),evts,data)

Documentation

Most functions have documentation, e.g. ?Unfold.fit

Tutorials see the documentation

Contributors (alphabetically)

  • Phillip Alday
  • Benedikt Ehinger
  • Dave Kleinschmidt
  • Judith Schepers
  • Felix Schröder
  • René Skukies

Acknowledgements

This work was supported by the Center for Interdisciplinary Research, Bielefeld (ZiF) Cooperation Group "Statistical models for psychological and linguistic data".

Funded by Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany´s Excellence Strategy – EXC 2075 – 390740016

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